		      Circulatory/Immune Norns
			   Version 1.0
			   Creatures 3

Overview:

Creatures 3 was a vast improvement in many areas, but one area in particular
lagged below my expectations; the immune system. It's very doubtful that CL
could have done anything to satiate my desire for a more accurate model of
the immune system. Which is why the immune genome for C3 was made. Because
I'm a freak with way too much free time. Basically this gives the norns
a circulatory system and an immune system. This should prove that a more
realistic model is often better, now that real immune processes are simulated
real immunity will develop. All too often a creature will get infected with
one disease, pass the disease along, recover from it, and get infected again
by a creature it just passed it to.

Specifics:

First and foremost, there are now different types of pathogens, each with
their own special symptoms. Bacteria (antigen 0) are your typical bad guys,
running amok reproducing and spreading their toxic waste these guys are not
to be messed with, their effects are fever and histamines along with the 
usual internal damage. Protozoa (antigen 1) are similar to bacteria,
but instead of fever toxin they release sleep toxin. DNA encoding viruses
(antigen 2) run rampant causing cellular damage and triggering histamine 
release. RNA encoding viruses (antigen 3) are similar to DNA encoding 
viruses, but they take a little longer for symptoms to manifest themselves 
and are harder to kill off as they have much greater mutability. External
fungus (antigen 4) is just an annoying infestation. It is difficult to get
rid of, but will generally not be fatal. Norns infested with this will have
elevated levels of histamines. Internal fungus (antigen 5) is a far nastier
prospect. Liquifying tissue with their digestive enzymes before consuming it,
this disease can leave norns exhausted and suffering from internal damage.
Parasites (antigen 6) are not a pretty sight at all. The damage they create
is similar to Internal fungus, but they breed slower and are much harder to
eliminate. Once a norn is infected with parasites it will be in for a long
battle. Be sure to think in terms of the long haul when dealing with this
illness. (In reality, the immune system has almost no chance of eliminating
established parasites. Norns are much more fortunate)Prions (antigen 7) are a 
unique illness. This is the only pathogen that is both infectious and 
genetic. These misfolded proteins seem harmless, they don't cause any 
symptoms at all, they don't release toxins or infect other cells or siphon
off food. All they do is go about refolding other proteins into replicas of 
themselves. Other than a negligable protein shortage, this would not be a 
problem. Except that when they refold a protein they make it insoluble. 
These insoluble proteins form plaques. These plaques push against neurons,
killing them. Eventually large areas devoid of brain activity develop. This
is invariably fatal in reality, but simulated life forms have better luck.
These creatures also have a circulatory system added. The components of the
"blood" are red blood cells, platlets, and immune components. Red Blood Cells
act as carriers of oxygen, each can hold 16 molecules of oxygen, effectively
increasing a norn's time without air by a factor of 16. The reaction rate is
tied to how much oxygen a creature has. If it falls too low the speed at 
which oxygen is released will increase. Platlets will stop creatures from
bleeding, yes these creatures do bleed when injured. Immune cells are a much
longer list, macrophages consume pathogens and cellular debris. Natural
killer cells destroy damaged cells. Neutrophils go about destroying pathogens
and diseased cells. T-cells and B-cells sit around waiting for macrophages
to present the antigen to them. Of all the trillions of T and B-cells, only
one of each is matched to a specific antigen. Once the antigen is recognized
by the appropriate T or B cell a process of clonal selection occurs in which
the cell multiplies at a very accelerated rate. T-cells will then enter the
blood stream and kill off the pathogen and any infected cells, while B-cells
will produce antibodies that will hinder the pathogen.

Even more specific specifics:

If you want to moniter the levels of all the various new chemicals, you can
use a monitering device to check the levels of the following chemicals

Invaders:

Bacteria (Antigen 0)
Protozoa (Antigen 1)
DNA encoded viruses (Antigen 2)
RNA encoded viruses (Antigen 3)
External Fungus (Antigen 4)
Internal Fungus (Antigen 5)
Parasites (Antigen 6)
Prions (Antigen 7)

Blood, Bone, and Thymus Components:

Red Blood Cells (220)		Blood cells carrying oxygen
Empty Red blood cells (221)	Blood cells without oxygen
Stem cells (222)		Undifferentiated cells that will differentiate to make up the immune and circulatory cells
Immune stem cells (223)		Same as above, but will only differentiate into immune cells
Platlets (224)			Blood component that clots injuries

Immune System Components:

Macrophages (225)		Absorbs cell debris and pathogens, ands acts as MHCs to deliver antigens to T and B cells
Natural Killer Cells (226)	Destroys damaged cells
Neutrophil (228)		Directly destroys pathogens, causes collateral damage
B-Cells (229)			Cells that through clonal selection will differentiate into imprinted B-cells
T-Cells (230)			Cells that through clonal selection will differentiate into imprinted T-cells
Imprinted B-cell 0 (233)	B-cell imprinted to prduce antibodies for Antigen 0
Imprinted B-cell 1 (234)	B-cell imprinted to prduce antibodies for Antigen 1
Imprinted B-cell 2 (235)	B-cell imprinted to prduce antibodies for Antigen 2
Imprinted B-cell 3 (236)	B-cell imprinted to prduce antibodies for Antigen 3
Imprinted B-cell 4 (237)	B-cell imprinted to prduce antibodies for Antigen 4
Imprinted B-cell 5 (238)	B-cell imprinted to prduce antibodies for Antigen 5
Imprinted B-cell 6 (239)	B-cell imprinted to prduce antibodies for Antigen 6
Imprinted B-cell 7 (240)	B-cell imprinted to prduce antibodies for Antigen 7
Imprinted T-cell 0 (241)	T-cell imprinted to eliminate Antigen 0
Imprinted T-cell 1 (242)	T-cell imprinted to eliminate Antigen 1
Imprinted T-cell 2 (243)	T-cell imprinted to eliminate Antigen 2
Imprinted T-cell 3 (244)	T-cell imprinted to eliminate Antigen 3
Imprinted T-cell 4 (245)	T-cell imprinted to eliminate Antigen 4
Imprinted T-cell 5 (246)	T-cell imprinted to eliminate Antigen 5
Imprinted T-cell 6 (247)	T-cell imprinted to eliminate Antigen 6
Imprinted T-cell 7 (248) 	T-cell imprinted to eliminate Antigen 7

Indicator Components:

Internal Damage (249)		Indication of bleeding, produced through injury
Collateral Damage (250)		A by-product of the cell-mediated immune response

